You're using an older version of Internet Explorer that is no longer supported. Please update your browser.
You're using an older version of Internet Explorer and some functionality may not work as expected. Please update your browser for the best experience.

Research Associate - Process Development

Reference ID: 109682

Share job:



Evonik Industries, its Burnaby, B.C. site, specializes in parenteral formulation development and manufacturing process design and implementation at small, intermediate, and large/commercial scales. This enables manufacturing of complex lipid-based formulations of therapeutic agents for preclinical and clinical testing in its state-of-the-art R&D and manufacturing facilities and transfer of drug product manufacturing to commercial facilities. Core manufacturing technologies include liposome extrusion, micro-mixing, tangential flow filtration (TFF) and sterile filtration with availability of small to large-scale equipment.

The site currently has an opening for a Research Associate - Process Development position, responsible for the development and scale-up manufacturing of lipid nanoparticle-based drug formulations and technology transfer to GMP production.

 Specific Responsibilities:

  •  Scale up and evaluate manufacturing processes at the 100 mL to 100 L scale;
  • Perform quantitative analyses on formulations and processes and analyze data;
  • Transfer manufacturing processes from R&D to Process Development and from Process Development to GMP production;
  • Support all aspects of the manufacture of Test Articles for use in GLP toxicology studies as well as Drug Products prepared in the GMP suite;
  • Closely work with the in-house Research, Analytical and GMP manufacturing groups;
  • Perform equipment DQ/IQ/OQ/PQ;
  • Prepare process equipment and buffer solutions (including large volumes);
  • Assist with inventory control and supply chain activities;
  • Prepare protocols, technical reports, data summaries and presentations. 
  • Effectively communicate in oral and/or written form to internal and external audiences;
  • Prepare, review and update laboratory procedures as required
  • Perform other duties as assigned

 Qualifications:

  •  BSc or MSc degree in Chemistry, Pharmaceutical Sciences, Chemical Engineering, Engineering or related field with a minimum of 3 years of work experience related to formulation development, process development, manufacturing or a related relevant field (industry experience preferred).
  • Experience with general laboratory instrumentation and techniques including aseptic methods;
  • Understanding of experimental design;
  • Mechanically inclined; adept at troubleshooting plumbing and electrical issues;
  • Work involves some heavy lifting (up to 50 kg) and maneuver large heavy equipment on wheels;
  • Basic knowledge of GMP and CMC regulatory requirements;
  • Must possess strong problem solving, organizational, and documentation skills with a focus on details and results;
  • Ability to work independently as well as in a team;
  • The candidate should be self-motivated and possess good interpersonal, collaborative, and communication skills. 

 


Posted: November 13, 2018
Closes: January 12, 2019